几丁糖酯原料药稳定性研究

该文建立高效凝胶渗透色谱法 (HPGPC) ,明胶比浊法 ,氧瓶燃烧法三种分析方法考察海洋硫酸多糖药物几丁糖酯的稳定性 ,采用这三种方法分别考察几丁糖酯原料药在高温、高湿、强光照射及加速条件下分子量及分布宽度、样品中硫酸根含量及样品含量的变化情况。结果表明 :三种方法均适用于几丁糖酯的稳定性考察 ,几丁糖酯在上述影响因素条件下稳定性良好     

福建闽南沿海养殖贝类体中砷含量的分布

通过2003~2004年对福建闽南沿海5种养殖贝类体砷含量的调查监测,对养殖贝类体中砷含量的分布进行了探讨.福建闽南沿海5种养殖贝类体总砷含量为0.65×10-6~4.80×10-6,总平均值为2.09×10-6,其中有机砷和无机砷占总砷含量的百分比分别为61.6%~98.2%和2.3%~38.4%,平均值分别为88.8%和11.2%.在相同养殖区,养殖贝类体总砷平均含量的种间分布差异较小.滩涂养殖底栖贝类体内总砷平均含量总体上高于浅海筏式养殖贝类体的平均含量.福建闽南沿海5种养殖贝类体内总砷含量在泉州湾、湄州湾、东山湾和九龙江口高,在诏安湾和围头湾低,在其余各湾相近.5种养殖贝类体内无机砷的污染指数和总平均值分别为0.05~0.76和0.23,总砷的污染指数和总平均值分别为0.06~0.48和0.21,总体符合国家食品卫生质量标准.养殖贝类体中砷含量与体长之间总体成正相关.     

Crustal Thinning of the Northern Continental Margin of the South China Sea

Magnetic data suggest that the distribution of the oceanic crust in the northern South China Sea (SCS) may extend to about 21 °N and 118.5 °E. To examine the crustal features of the corresponding continent–ocean transition zone, we have studied the crustal structures of the northern continental margin of the SCS. We have also performed gravity modeling by using a simple four-layer crustal model to understand the geometry of the Moho surface and the crustal thicknesses beneath this transition zone. In general, we can distinguish the crustal structures of the study area into the continental crust, the thinned continental crust, and the oceanic crust. However, some volcanic intrusions or extrusions exist. Our results indicate the existence of oceanic crust in the northernmost SCS as observed by magnetic data. Accordingly, we have moved the continent–ocean boundary (COB) in the northeastern SCS from about 19 °N and 119.5 °E to 21 °N and 118.5 °E. Morphologically, the new COB is located along the base of the continental slope. The southeastward thinning of the continental crust in the study area is prominent. The average value of crustal thinning factor of the thinned continental crust zone is about 1.3–1.5. In the study region, the Moho depths generally vary from ca. 28 km to ca. 12 km and the crustal thicknesses vary from ca. 24 km to ca. 6 km; a regional maximum exists around the Dongsha Island. Our gravity modeling has shown that the oceanic crust in the northern SCS is slightly thicker than normal oceanic crust. This situation could be ascribed to the post-spreading volcanism or underplating in this region.     

A STUDY OF MICROTEKTITES IN THE PACIFIC OCEAN

In 1979, we found many small colorless transparent and light yellow-green glassy spherules in the surface layer and core sediment samples taken from the west of the Central Pacific Occan, which are considered to be microtektites. This finding is worthy of further determination of the range of strewn field and origin of tektites.     

埕岛油田海区海底地形变化及预防措施

综合在胜利石油管理局埕岛油田海区多年来工程测绘与地质勘察资料 ,对埕岛油田海区地形地貌特征及其变化与发育趋势进行了论述 ,同时讨论了埕岛油田海上工程中需要重视的问题以及有关的工程防护问题。     

碘－钒盐催化下合成的四溴邻苯二甲酸酐

报道一种新的有效催化剂－碘－钒盐和在一定条件下合成四溴邻苯二甲酸酐的方法。探讨催化剂的组成配比、用量、温度及废酸循环使用等因素对合成方法的影响。该催化剂的催化效果和常用的碘、碘－铁催化剂相同，适用于四溴邻苯二甲酸酐的合成。     

珠江口盆地基底结构的综合地球物理研究

通过对珠江口盆地重磁资料的分析处理及反演计算，依据盆地的地质、地球物理特征，采取了针对性的综合地球物理研究思路与方法，对地震资料难以解决的珠江口盆地基底结构进行了研究，确定了盆地的重力和磁性基底深度，并对盆地内的断裂和基底岩性作了推断，提供了新的认识，为今后研究提供了依据。     

合浦珠母贝卵子电击脉冲参数的初步研究

运用电脉冲转基因仪对合浦珠母贝卵子进行电脉冲处理以优化电穿孔法转基因的电击参数。实验中调制百分比：100％；脉冲间隔：1．0s：电极距离：2mm；脉冲个数：5个，参数保持不变。用不同的电脉冲参数组合（脉冲电压100-400V、脉冲持续时间0．5～3．0ms、脉冲频率10～50kHz，共28个组合）对卵子电击，然后加入精子进行授精，统计各组受精率和孵化率，以受精率和孵化率达到50％以上为衡量指标。结果表明，合浦珠母贝卵子对低脉冲频率和高电压非常敏感，当频率低于20kHz或脉冲电压高于400V时对卵子损伤较大。脉冲持续时间对其影响不大，适应范围较宽。优化的转基因电击脉冲参教组合为：脉冲电压1.0kV／cm，脉冲持续时间20ms，脉冲频率50kHz，或者脉冲电压1．5kV／cm，脉冲持续时间1．5ms，脉冲频率50kHz。     

哈维氏弧菌的生物学特性、流行病学及检测技术

哈维氏弧菌是1种革兰氏阴性、发光的海洋细菌,广泛分布于海洋环境中。它是最近10多年才被认识到的水产养殖动物的重要致病菌。文中综述哈维氏弧菌的生物学特性、流行病学、致病机制、密度感应系统、检测技术、疾病的防治及其应用。     

进入渤海的热带气旋路径特点分析

热带气旋是夏季影响渤海的灾害性天气系统之一。其影响路径主要有三类，各类路径在影响时前期中高纬500hPa高空环流形势及夏季西太平洋副热带高压特征指数有显著差异。